CtrlPoint
Manufacturing intelligence · Pharmaceutical operations

The Future Of
Pharma Manufacturing

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Most MES was written
as a system of record.
CtrlPoint was written
as an instrument.

Paper batch records were faithfully digitized. Twice. Neither pass gave manufacturing engineers what they actually needed - a live, queryable model of the plant.

We started from the operator's tablet, the equipment layer, and the audit trail - then built the record upward. What emerges looks like an EBR. It behaves like an operating system.

Electronic Batch Records
Designed For The Production Floor

View platform
CtrlPoint · Electronic Batch Record
Batch No.B-2026-004817ProductParacetamol 500 mgLineCompression 02PhaseCompressionStep14 / 32OperatorM. Okoye
StatusLive
Batch steps
Step 14 · Compression · Active

Compression start-up verification

Est. 4:12 · Elapsed 2:47
Instruction

Verify that the tablet press has been cleared, configured, and released for the current batch. Confirm the approved tooling set is installed and complete the initial tablet checks before starting routine compression.

Equipment
Tablet Press TP-201
Tooling Set
TS-500-02
Line Clearance
Complete
Live process signal · Compression start-up verification
Target 500 mg · Limits 490-510 mg
USL 510LSL 490
Average Weight
499.2 mg
Tablet Thickness
4.8 mm
Tablet Hardness
8.4 kp
Electronic signatures
Performed By
M. Okoye
06:12:41Z
Verified By
Pending
-
Activity timeline
  • 06:12:41ZStep 13 · Equipment setup completed - M. Okoye
  • 06:10:18ZTooling set TS-500-02 verified - M. Okoye
  • 06:07:52ZLine clearance approved - R. Duarte
  • 06:03:26ZTablet press TP-201 assigned to B-2026-004817
  • 05:58:11ZCompression phase released - Production Supervisor
Capability
Electronic Signatures

Every completed action is linked to the authenticated user, signature meaning, date, and time, creating a clear and attributable manufacturing record.

Capability
Exceptions In Context

Out-of-limit values and process issues are recorded directly against the affected batch step, with the original entry, justification, and follow-up actions preserved.

Capability
Live Process Data

Critical process parameters can be captured directly from connected equipment and linked automatically to the correct batch, phase, and manufacturing step.

One Connected Platform
For Manufacturing Operations

CtrlPoint connects batch execution, equipment history, quality review, and manufacturing intelligence in one controlled environment.

Approved MBRLive batchEquipment useExceptionQA reviewIntelligence
EBR
Electronic Batch Records

Master Batch Records authored once, executed live on the floor.

E-Logs
Electronic Logbooks

Every equipment, room, and area carries its own controlled digital history.

Intelligence
Manufacturing Intelligence

Structured batch and equipment data becomes trend, yield, and deviation insight.

FoundationsUnique user identityRole-based accessElectronic signaturesImmutable audit trailEquipment registryStructured manufacturing dataNotifications & review

Every Equipment Event.
Recorded Digitally.

Equipment
High-Shear Granulator GR-201
Solid Dose · Granulation Room 02
Current status · Clean
Equipment ID
GR-201
Cleaning Valid Until
18 Jul 2026 · 14:30
Calibration
Valid · Next 05 Sep 2026
Current Batch
None
Logbook · last 24 hours
  • 10 Jul · 14:21
    Cleaning completed
    SOP CLN-114 v6 · Performed A. Rahman · Verified S. Patel
  • 10 Jul · 11:48
    Batch B-2026-004817 completed
    Equipment use closed
  • 10 Jul · 06:03
    Equipment use started
    Batch B-2026-004817 · Granulation phase
  • 09 Jul · 17:12
    Pre-use inspection completed
    Checklist PUI-08 · S. Patel
  • 09 Jul · 15:44
    Gasket replaced
    Maintenance event MT-2041 · Engineering
Status lifecycle
  • 01Available
  • 02In Use
  • 03Cleaning Required
  • 04Clean
  • 05Under Maintenance

Status transitions occur automatically when the associated manufacturing activity begins, ends, or requires cleaning verification.

Capability
Equipment Use History

Every use is linked automatically to the relevant batch, operator, date, and time.

Capability
Cleaning & Verification

Cleaning records capture the approved SOP, cleaning details, and independent electronic verification.

Capability
Calibration & Maintenance

Due dates, maintenance events, and equipment availability remain visible throughout manufacturing.

See The Manufacturing Floor
As It Happens

Active production lines
Line 01
B-2026-004812
Granulation
64% Complete
On Schedule
Line 02
B-2026-004817
Compression
38% Complete
1 Open Exception
Line 03
-
Cleaning In Progress
-
Clean Hold Starts In 18 min
Line 04
B-2026-004819
Awaiting 2nd-Person Verification
100% Complete
Waiting · Supervisor
Equipment · site total
  • Available18
  • In Use7
  • Cleaning Required4
  • Under Maintenance2
  • Out Of Service1
Attention
  • · 2 units cleaning validity expires within 8 h
  • · 1 balance calibration due in 3 days
  • · 3 batches waiting for QA review

Every Manufacturing Record.
Connected.

QA can open every record without moving between systems or paper files. Line clearance links to the batch. The batch links to the equipment. The equipment links to its cleaning record. The room links to environmental readings.

Record types
Equipment UseEquipment CleaningRoom CleaningEnvironmental MonitoringLine ClearanceCalibrationMaintenanceShift Handover
Every record carries
  • · Batch
  • · Equipment
  • · Room
  • · User
  • · Signature
  • · Date & time
Preview
Line clearance · Compression Line 02
Batch B-2026-004817
  • Previous product and labels removed
  • Previous batch materials removed
  • Area cleaned and inspected
  • Equipment status verified
  • Documents from the previous batch removed
  • Correct batch documentation available
Performed By
R. Duarte · 06:07:52Z
Verified By
S. Patel · 06:08:41Z

Review What Matters.
Release With Confidence.

CtrlPoint · QA Review
BatchB-2026-004817ProductParacetamol 500 mgMBR Versionv4.2StatusAwaiting QA Review
Phases
  • Dispensing
  • Granulation
  • Drying
  • Blending
  • Compression3
  • Coating
  • Packaging
Batch summary
Completed Steps
32 / 32
Required Signatures
47 / 47
Material Entries
6 / 6 Verified
Exceptions
3
Open Queries
0
Open Deviations
0
Note

The complete record remains available for review. CtrlPoint directs attention to entries requiring quality judgement - corrections, exceptions, manual entries, and unresolved queries.

Items requiring review
  • Tablet weight outside alert limit
    Review
    Step 15 · Compression
    Entered
    511.2 mg
    Approved range
    490–510 mg
    Justification
    Reading confirmed, sample retained.
    Supervisor
    Accepted with comment
  • Manual parameter entry
    Review
    Step 18 · Compression
    Reason
    Tablet press connection temporarily unavailable
    Entered by
    M. Okoye
  • Late IPC reading
    Review
    Step 22 · Compression
    Due
    10:30
    Recorded
    10:38
Capability
Review By Exception

Quality teams are guided directly to exceptions, corrections, missing signatures, and unresolved queries.

Capability
Complete Traceability

Every value, signature, correction, and linked record remains available in its original context.

Capability
Controlled Disposition

Release, rejection, and hold decisions follow defined permissions, checks, and electronic signatures.

From Equipment
Directly Into The Batch Record

Equipment
  • TP-201
    Tablet Press
  • WB-01-B1
    Balance
  • GR-201
    High-Shear Granulator
  • CP-301
    Coating Pan
  • RM-02
    Environmental Sensor
Live values into batch steps
  • Tablet Weight
    TP-201 · captured 06:14:22Z
    499.2 mg
    Compression · Step 15
  • Compression Force
    TP-201 · captured 06:14:22Z
    18.4 kN
    Compression · Step 15
  • Granulation Temperature
    GR-201 · captured 06:14:22Z
    41.8 °C
    Granulation · Step 06
  • Impeller Speed
    GR-201 · captured 06:14:22Z
    185 rpm
    Granulation · Step 06
  • Room Differential Pressure
    RM-02 · captured 06:14:22Z
    15 Pa
    Environmental · Continuous
Fallback
Manual Entry · Reason Required

When a connection is unavailable, the operator enters the value manually and records a reason. The entry is flagged for QA review.

Protocols
  • OPC UA
  • Modbus
  • REST API
  • Historian
  • Edge Gateway

Every value carries its equipment source, capture time, batch, phase, and step - traceable from the batch record back to the machine that produced it.

Manufacturing Intelligence
Built From Every Batch

Process parameter trend
Drift · monitor
Granulation Endpoint Torque
Last 20 batches · Specification 3.0–4.2 Nm
USL 4.2 NmLSL 3.0 Nm
Current Trend
Increasing
Projected Limit Risk
Within 7 batches
Root Signals
Impeller wear · load variance
Yield analysis
97.8%
Average yield · last 90 days
Predicted · active batch
96.9 – 97.6%
Confidence · high
Key influencing parameters
  • · Granulation moisture
  • · Compression reject rate
  • · Coating weight gain
Recurring deviation pattern
Incorrect Tooling Setup
  • Occurrences4 in 90 days
  • Affected equipmentTablet Press TP-201
  • Previous CAPAEffectiveness concern
Equipment health
62
/ 100 · Monitor
Granulator GR-201
  • · Increasing motor current variability
  • · Two recent deviations
  • · Maintenance due in 18 days
Ask · manufacturing question
Question

Which production line had the highest number of compression-related exceptions during the last six months?

Answer

Compression Line 02 recorded 14 exceptions across 28 completed batches. Eight were linked to tablet-weight variability.

AI supports investigation, prioritization, prediction, and reporting. Final GMP decisions remain with authorized users.

Compliance Is Not
An Add-On.

Foundational capabilities
  • Unique user identity
  • Role-based access
  • Electronic signatures
  • Immutable audit trail
  • Version-controlled Master Batch Records
  • Reason-for-change
  • Controlled review and approval
  • Secure record retention
  • Search and retrieval
  • Locked PDF export
Aligned standards
21 CFRPart 11
EUAnnex 11
GAMP5
ALCOA+Data Integrity
ISA-95Aligned

Designed to support compliant electronic records and signatures. Built around attributable, legible, contemporaneous, original, and accurate records. Configuration and validation remain controlled within each customer implementation.

One Platform.
Built Around The Work.

Operator · navigation
  • Active batch
  • My tasks
  • Machine values
  • Signatures
  • Raise exception
Primary task
Compression start-up verification
Batch B-2026-004817 · Step 14 / 32
  • ·Verify tooling set TS-500-02
  • ·Enter tablet weight (start-up check)
  • ·Confirm line clearance is complete
  • ·Apply performed-by signature

See CtrlPoint
In Your Manufacturing Environment

Explore how Electronic Batch Records, Electronic Logbooks, equipment connectivity, and manufacturing intelligence can work together across your operation.